Research Article Open Access

CHEMICAL COMPOSITION, ANTIMICROBIAL, ANTIOXIDANT AND CYTOTOXIC ACTIVITIES OF EUCALYPTUS CHAPMANIANA GROWN IN IRAQ

Ghassan Mohammad Sulaiman1, Thorria Radam Marzoog1, Wasnaa Hatif Mohammed1 and Renzo Bagnati2
  • 1 Division of Biotechnology, Department of Applied Science, University of Technology, Baghdad, Iraq
  • 2 Department of Environmental Health Sciences, IRCCS-Istituto di Ricerche Farmacologiche Mario Negri, Via La Masa 19, 20156 Milano, Italy

Abstract

The chemical composition of the essential oils extracted from immature flowers, leaves and seeds of Eucalyptus chapmaniana grown in Iraq were analyzed for the first time by gas chromatography/mass spectrometry. Twenty-four different compounds were identified and the predominant compound is eucalyptol, which accounted for 59.9, 55.6 and 8.6% of total compounds, respectively. To asses the possible therapeutic uses of the extracts, their antioxidant properties were assessed via DPPH free radical scavenging. The extracts showed significant antioxidant and antimicrobial activities against Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Proteus volgaris, Staphylococcus aureus and Candida albicans. The cytoxicity of flower extract against the Human Leukemia (HL-60) cells was evaluated and the extracts significantly reduced the viability of HL-60 cells in a dose- and time-dependent response relationship. The results indicated that essential oils from immature flowers are highly cytotoxic to HL-60 cells and that their antitumor potential was confirmed.

American Journal of Agricultural and Biological Sciences
Volume 9 No. 1, 2014, 78-88

DOI: https://doi.org/10.3844/ajabssp.2014.78.88

Submitted On: 31 October 2013 Published On: 27 December 2013

How to Cite: Sulaiman, G. M., Marzoog, T. R., Mohammed, W. H. & Bagnati, R. (2014). CHEMICAL COMPOSITION, ANTIMICROBIAL, ANTIOXIDANT AND CYTOTOXIC ACTIVITIES OF EUCALYPTUS CHAPMANIANA GROWN IN IRAQ. American Journal of Agricultural and Biological Sciences, 9(1), 78-88. https://doi.org/10.3844/ajabssp.2014.78.88

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Keywords

  • Eucalyptus chapmaniana
  • Essential Oils
  • Antimicrobial
  • DPPH
  • HL-60