American Journal of Pharmacology and Toxicology

Micronutrients, Hormesis and the Aptitude for the Maturation of Regulation

Jaap C. Hanekamp

DOI : 10.3844/ajptsp.2008.144.151

American Journal of Pharmacology and Toxicology

Volume 3, Issue 1

Pages 144-151


The potential of hormesis as the default model to assess and manage chemicals is considered in relation to micronutrients. It is pointed out that micronutrients, despite their well-known U-shaped dose-response curve, are assessed and managed only with excess-exposure in mind. Hereby a schism between health and safety is unjustifiably realized. This proves to be the conundrum of basically all chemicals regulation. It is proposed that hormesis could in principle address this conundrum.


© 2008 Jaap C. Hanekamp. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.