American Journal of Pharmacology and Toxicology

Life Extension by Anti-Aging Drugs: Hormetic Explanation?

A.M. Vaiserman

DOI : 10.3844/ajptsp.2008.14.18

American Journal of Pharmacology and Toxicology

Volume 3, Issue 1

Pages 14-18


A number of chemicals including antioxidants, vitamins and hormones are widely advertised as anti-aging drugs (geroprotectors). It is usually believed that life-extending capacity of geroprotectors may be attributed to their specific anti-aging mechanisms, even without solid scientific evidence. The analysis of the survival data gathered by both anti-aging and hormetic interventions demonstrates that many essential similarities exist between them. The evidence that life-extending effects of anti-aging drugs may be due to hormetic-like response is discussed in this review.


© 2008 A.M. Vaiserman. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.