Research Article Open Access

Use of an Extremely Biodiverse Probiotic and a Supplement Based on Microbial Chondroitin Sulfate is Associated with a Significant Decrease of Serum Free Kappa Light Chains as well as a Trend Toward Normalization of Kappa/Lambda Ratio and of Plasma Cell Bone Marrow Infiltration in a Case of Multiple Myeloma

Nicola Antonucci1, Stefania Pacini2 and Marco Ruggiero2
  • 1 Biomedical Centre for Autism Research and Treatment, Italy
  • 2 Silver Spring Sagl, Switzerland

Abstract

We describe the case of a 71-year-old woman with multiple myeloma associated with severe chronic renal insufficiency who, since October 2018, assumed a novel, extremely biodiverse, probiotic and a supplement based on microbial chondroitin sulfate, vitamin D3 and ultrapure phosphatidylcholine; such a nutritional regimen was associated with a dramatic decrease of serum free Kappa light chains (from 2,190 to a minimum of 119.40 mg/L) as well as a trend toward normalization of Kappa/Lambda ratio (from 187 to a minimum of 3.16) and of plasma cell bone marrow infiltration (from 20 to 5%).

American Journal of Immunology
Volume 15 No. 1, 2019, 5-9

DOI: https://doi.org/10.3844/ajisp.2019.5.9

Submitted On: 27 May 2019 Published On: 18 June 2019

How to Cite: Antonucci, N., Pacini, S. & Ruggiero, M. (2019). Use of an Extremely Biodiverse Probiotic and a Supplement Based on Microbial Chondroitin Sulfate is Associated with a Significant Decrease of Serum Free Kappa Light Chains as well as a Trend Toward Normalization of Kappa/Lambda Ratio and of Plasma Cell Bone Marrow Infiltration in a Case of Multiple Myeloma. American Journal of Immunology, 15(1), 5-9. https://doi.org/10.3844/ajisp.2019.5.9

  • 3,012 Views
  • 1,326 Downloads
  • 0 Citations

Download

Keywords

  • Colostrum
  • Phages
  • Probiotic
  • Multiple Myeloma
  • Chondroitin Sulfate
  • Vitamin D3
  • Phosphatidylcholine
  • RAD52