American Journal of Immunology

β-Glucan in Allergies

Sima Petr and Vetvicka Vaclav

DOI : 10.3844/ajisp.2017.73.80

American Journal of Immunology

Volume 13, Issue 1

Pages 73-80


Multiple effects of β-glucan are well established. Together with the effects on antibacterial and anticancer immunity, glucan has been shown to stimulate bone marrow cells, lower cholesterol and to protects against stress and some kinds of poisoning. However, despite literally thousands of papers describing biological effects of β-glucan, only limited attention has been focused on the role of β-glucan in allergic reactions. Our review is focused on evaluating the current knowledge of the possible role of β-glucan in allergic reactions. Most of published studies concur that based on the improved Th1/Th2 balance, β-glucan showed a potential for development as an adjunct to the standard treatment of in patients with allergies.


© 2017 Sima Petr and Vetvicka Vaclav. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.