American Journal of Immunology

Like an Invertebrate Primitive Antibody

Michel Leclerc

DOI : 10.3844/ajisp.2013.94.95

American Journal of Immunology

Volume 9, Issue 3

Pages 94-95


Specific immune responses occur in an invertebrate: The sea star Asterias rubens. Sea star T and B lymphocytes are present in the axial organ and coopere with phagocytes and Complement components to produce a primitive antibody correlated to Igkappa genes and to complement genes: It could be composed of 4 kappa chains and present strong and highly significant homologies to Mouse IgKappa region V-IV S107B precursor gene.


© 2013 Michel Leclerc. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.