American Journal of Immunology

β 1, 3-Glucan in Cancer Treatment

Vaclav Vetvicka and J. Vetvickova

DOI : 10.3844/ajisp.2012.38.43

American Journal of Immunology

Volume 8, Issue 2

Pages 38-43


Natural products, useful in preventing and/or treating various diseases, have been sought after throughout the man’s history. Despite some problems inherited from the natural source of glucans, there is extensive literature about their activities in animal tumor models. For the past 25 years, Japan has used several forms of mushroom-derived glucans in treating cancer patients. Additionally, close to twenty clinical trials are currently running in several countries, further suggesting the strong possibility of using glucans as an established anti-cancer drug.


© 2012 Vaclav Vetvicka and J. Vetvickova. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.