American Journal of Immunology

An Analysis of the Creatine Kinase Isoenzyme and Cardiac Troponin T Levels in a Polymyositis Patient

R.M. Golding, L.G.F. Giles and E.M. Sokoya

DOI : 10.3844/ajisp.2008.1.7

American Journal of Immunology

Volume 4, Issue 1

Pages 1-7


From an extensive model developed to interpret physiological processes we are able to show that the observed elevated creatine kinase-myoglobin (CK-MB) and serum concentration of cardiac troponin T (cTnT) values for a particular patient are associated with the inflammatory disease, polymyositis, and not myocardial injury. This highlights that caution must be exercised in using elevated CK-MB and cTnT levels as evidence for myocardial damage in patients with chronic muscle degeneration such as polymyositis.


© 2008 R.M. Golding, L.G.F. Giles and E.M. Sokoya. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.