American Journal of Immunology

The immunological aspects of Acanthamoeba infections

Naveed A. Khan

DOI : 10.3844/ajisp.2005.24.30

American Journal of Immunology

Volume 1, Issue 1

Pages 24-30


Acanthamoeba is a protozoan pathogen that is responsible for two recognized diseases; i) a blinding keratitis, most commonly associated with contact lens wear, and ii) a rare but fatal granulomatous encephalitis that usually is limited to immunocompromised patients. The fact that Acanthamoeba infections are generally limited to avascular cornea or immunocompromised patients suggests that the normal immune responses may be sufficient to control and/or eradicate these pathogens. Here we describe our current understanding of the immune responses to Acanthamoeba infections.


© 2005 Naveed A. Khan. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.