American Journal of Infectious Diseases

Granulomatous Amoebic Encephalitis: Clinical Diagnosis and Management

Naveed Ahmed Khan

DOI : 10.3844/ajidsp.2005.79.83

American Journal of Infectious Diseases

Volume 1, Issue 2

Pages 79-83


Granulomatous amoebic encephalitis (GAE) is a serious human disease with fatal consequences. With the mortality rate of more than 90%, it is not surprising that the majority of GAE infections are identified at the post-mortem stage. The most distressing aspect is that the high level of mortality is attributed to lack of awareness. Early diagnosis with aggressive treatment can lead to successful prognosis for the patient. Here, we describe a brief overview of the current understanding of the pathophysiology of GAE, available diagnostic methods, possible therapeutic interventions and the causative agents.


© 2005 Naveed Ahmed Khan. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.