@article {10.3844/ojbsci.2013.66.71,
article_type = {journal},
title = {IMMUNOHISTOCHEMICAL ANALYSIS OF UROTHELIAL BLADDER CANCERS},
author = {Bevizova, Katarina and Jakubovsky, Jan and Luha, Jan and Novakova, Zuzana Varchulova and Polak, Stefan},
volume = {13},
number = {2},
year = {2013},
month = {Jul},
pages = {66-71},
doi = {10.3844/ojbsci.2013.66.71},
url = {https://thescipub.com/abstract/ojbsci.2013.66.71},
abstract = {Malignant cancers of urinary bladder are the second most common malignancy of the urinary tract and the fourth most common malignancy in general, especially in men. The aim of this study was a retrospective analysis of selected markers (p53, Ki-67 and E-cadherin) of urinary bladder cancers from the Department of Urology in Bratislava, Slovak Republic between years 2007 and 2009. We analysed 244 patients (202 males, 42 females) with diagnosed bladder cancer via cystoscopy and subsequent transurethral resection. Patients’ age varied from 36 to 98 years. Obtained samples were fixed by 10% buffered formalin for 24 to 48 h. Subsequently, they were dehydrated in ascending ethanol series and embedded in paraffin. The parafin sections of 5 µm were prepared by microtome and they were stained by haematoxylin and eosin. The antibodies against to p53, Ki-67 and E-cadherin were used in immunohistochemical analysis. Statistical evaluation was performed via SPSS using non-parametric Kruskal-Wallis test and p values},
journal = {OnLine Journal of Biological Sciences},
publisher = {Science Publications}
}