TY - JOUR AU - Filip, R. AU - Harrison, A. AU - Pierzynowski, S. G. PY - 2007 TI - A Combined Phytohemagglutinin And α-Ketoglutarate Pharmacology Study of Gut Morphology and Growth in Older Adult Rats JF - American Journal of Pharmacology and Toxicology VL - 2 IS - 4 DO - 10.3844/ajptsp.2007.170.177 UR - https://thescipub.com/abstract/ajptsp.2007.170.177 AB - This study has evaluated the effect of phytohaemagglutinin (PHA) in combination with alpha-ketoglutaric acid (AKG), on GI-tract morphology and N balance in adult rats. Rats, aged approx. 15 months, were assigned to one of four experimental groups, (1) Control group, (2) AKG group, (3) AKG+PHA 100% group and (4) AKG+PHA 1% group. AKG and AKG+PHA were administered via a stomach tube. Rats were treated for a period of 7 days before being killed humanely. Lighter GI-tract weights were found in the AKG and AKG+PHA 1% groups (6.8%, p