@article {10.3844/ajisp.2020.1.7, article_type = {journal}, title = {NCCRP-1 Might Not be a Marker of so Called NCC Cells in Common Carp (Cyprinus carpio) Leukocytes}, author = {Shimon-Hophy, Mazal and Jacob, Avi and Avtalion, Ramy R.}, volume = {16}, year = {2020}, month = {Mar}, pages = {1-7}, doi = {10.3844/ajisp.2020.1.7}, url = {https://thescipub.com/abstract/ajisp.2020.1.7}, abstract = {The purpose of this study was to verify whether NCCRP-1 is a marker of a unique type of cells in teleost, so-called NCC, or an ubiquitin, like in cytotoxic cells. Therefore, common carp peripheral blood leukocytes were isolated and tested for the binding of fluorescent NCCRP-1 antibody to stained MAIT, γδ T and T cells following stress treatments. The results were analyzed by a confocal microscope. The results revealed the presence of NCCRP-1 in γδ T, MAIT and T cells in more than one type of leukocytes. γδ T cells were the dominant population in carp leukocytes. Therefore, it was concluded that there might be no presence of NCC cells in the common carp leukocytes and that the NCC marker,NCCRP-1, acts probably as an ubiquitin in cytotoxic cells such as γδ T and MAIT cells, which were abundant in peripheral blood leukocytes of common carp.}, journal = {American Journal of Immunology}, publisher = {Science Publications} }