TY  - JOUR
AU  - Lee, Ying-Ray 
AU  - Hung, Nguyen-Thanh 
AU  - Liu, Ching-Chuan 
AU  - Huang, Kao-Jean 
AU  - Lei, Huan-Yao 
AU  - Lin, Yee-Shin 
AU  - Wang, Jen-Reng 
AU  - Yeh, Trai-Ming 
AU  - Chen, Shun-Hua 
AU  - Liu, Hsiao-Sheng 
PY  - 2008
TI  - Correlation of IFN-Inducible Protein 10 Levels in Sera with Disease Severity and Clinical Outcome of the Dengue Patients
JF  - American Journal of Infectious Diseases
VL  - 4
IS  - 1
DO  - 10.3844/ajidsp.2008.18.21
UR  - https://thescipub.com/abstract/ajidsp.2008.18.21
AB  - Dengue Virus (DV) infection may cause life-threatening Dengue Hemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS). Although many cytokines involved in the pathogenesis of DHF/DSS have been reported, the expression status of IFN-inducible protein-10 (IP-10) in dengue patients is still unknown. This is the first report to unravel that IP-10 level was significantly elevated in the sera of Dengue Fever (DF) patients. However, the level declined while the disease proceeds to severe DHF/DSS, which is different from the expression profiles of other DV related cytokines in the patients. IP-10 may be used to monitor the severity of dengue disease.