@article {10.3844/ajbbsp.2010.84.88,
article_type = {journal},
title = {Apoptosis of human Breast Cancer Cells induced by Ethylacetate Extracts of Propolis},
author = {Syamsudin, and Simanjuntak, Partomuan and Djamil, Ratna and Heffen, Wan Lelly},
volume = {6},
number = {2},
year = {2010},
month = {Jun},
pages = {84-88},
doi = {10.3844/ajbbsp.2010.84.88},
url = {https://thescipub.com/abstract/ajbbsp.2010.84.88},
abstract = {Problem statement: Propolis has been ethno medically claimed to possess a wide array of biological activities including anticancer activity. The purpose of this research was to verify the folklore claim. Approach: This study was performed in a human breast carcinoma cell, MCF-7. Extract of propolis from different solvent, ethylacetate and n-buthanol showed induced apoptotic cells was detected by flow cytometry. Results: The results demonstrated that ethylacetate extract of propolis can induce apoptosis in MCF-7 as large as 13.21% during the 24 h incubation. On the other hand, doxorubicin is able to induce apoptosis as large as 18.89% during the 24 h incubation. Conclusion: The extracts of propolis ethylacetate had cytotoxic activity and triggers apoptosis on MCF-7 cells.},
journal = {American Journal of Biochemistry and Biotechnology},
publisher = {Science Publications}
}