TY - JOUR AU - Gyenai, Kwaku Barima AU - Worku, Mulumebet AU - Tajkarimi, Mehrdad AU - Ibrahim, Salam PY - 2016 TI - Influence of Probiotics on Coccidia, H. Contortus and Markers of Infection in Goats JF - American Journal of Animal and Veterinary Sciences VL - 11 IS - 3 DO - 10.3844/ajavsp.2016.91.99 UR - https://thescipub.com/abstract/ajavsp.2016.91.99 AB - Immunostimulants can induce nonspecific resistance against parasites. The use of probiotics to control development of animal gastrointestinal parasites could help reduce the risks of infestation. In this study, we investigated the effects of probiotics administration on gastrointestinal parasites coccidia, H. contortus and markers of infection. A cocktail of probiotics mix including Bifidobacterium longum, Bifidobacterium breve, Lactobacillus acidophilus, Lactobacillus reuteri and Lactobacillus rhamnosus (8.5 log CFU/mL) was drenched daily to three months-old male Spanish Boer kid-goats (n = 3) till four weeks of age. Control group of age matched kid-goats received sterile water daily for a 4-week period. Body weight, Fecal Egg Count, FAMACHA scores, Packed Cell Volume (PCV) and White Blood Cell Differential Count was determined weekly. Denaturing Gradient Gel Electrophoresis (DGGE) was used to monitor fecal bacteria using bacteria 16 sec rDNA primers. Pro-inflammatory cytokines, Prostaglandin2 (PGE2) and Immunoglobulin E levels in plasma were evaluated using commercial ELISAs. Results showed no significant difference in PCV, body weight, White Blood Cell Differential Count, FAMACHA score, PGE2 and IgE levels between probiotic drenched and control. However, eggs per gram were increased significantly (p