@article {10.3844/ajavsp.2015.23.35,
article_type = {journal},
title = {Hormonal and Histopathological Alterations in Pituitary Glands and Reproductive Organs of Male and Female Mice Orally Inoculated with Pasteurella Multocida Type B: 2 and its Lipopolysaccharides},
author = {Abdullah, Faez Firdaus Jesse and Adamu, Lawan and Tijjani, Abdulnasir and Mohammed, Konto and Abba, Yusuf and Sadiq, Muhammad Abubakar and Zainal, Rosmawati and Sabu, Muhammad Jamil Bin and Saharee, Abdul Aziz and Haron, Abdul Wahid},
volume = {10},
number = {1},
year = {2014},
month = {Dec},
pages = {23-35},
doi = {10.3844/ajavsp.2015.23.35},
url = {https://thescipub.com/abstract/ajavsp.2015.23.35},
abstract = {Oral infections of mice as animal model with Pasteurella multocida type B: 2 and its lipopolysaccharides is liable to cause detrimental alterations in the pituitary glands, which results in disruption of reproductive hormonal levels as well as organ functions in the male and female animals; thereby impeding the fertility of at risk animal population. Therefore, this study was designed to evaluate the histopathological modifications in the pituitary glands, reproductive organs and the associated hormonal levels in male and female mice inoculated orally with P. multocida type B: 2 and its lipopolysaccharides. Forty eight mice were divided into three groups consisting of sixteen mice each (8 male and 8 female in separate cages). Group 1 served as the control group and were inoculated orally with 0.4 mL Phosphate Buffer Saline (PBS), group 2 were inoculated orally with 0.4 mL of 109 Colony Forming Unit (CFU) of P. multocida type B: 2 while group 3 were inoculated orally with 0.4 mL of LPS from 109 of colony P. multocida type B: 2. There were significant differences (p},
journal = {American Journal of Animal and Veterinary Sciences},
publisher = {Science Publications}
}