TY  - JOUR
AU  - Loughmiller, J.A. 
AU  - Dritz, S.S. 
AU  - Nelssen, J.L. 
AU  - Tokach, M.D. 
AU  - Goodband, R. D. 
AU  - Moser, S.A. 
AU  - De La Llata, M. 
PY  - 2007
TI  - Effects of Salmonella typhimurium Challenge on Swine Growth, Nitrogen Balance, Insulin-like Growth Factor-I, and Acute Phase Proteins 
JF  - American Journal of Animal and Veterinary Sciences
VL  - 2
IS  - 1
DO  - 10.3844/ajavsp.2007.11.22
UR  - https://thescipub.com/abstract/ajavsp.2007.11.22
AB  - Growing barrows were used to determine the effects of an en teric disease challenge on nutrient balance, growth, acute phase proteins, and IGF-I. Pigs were challenged on d 0 with Salmonella typhimurium (S; N=21), or unchallenged and fed ad libitum (A; n=6), or unchallenged and pair-fed the same amount of feed as a challenged pig (P; n=8). Blood was collected on d -3, 1, 5, 9, and 15. A disease challenge &times; time interaction was observed for serum haptoglobin (P < 0.05), with greater haptoglobin for S vs A on d 1 and 5 (P < 0.05) and for S vs P on d 5 (P < 0.05). Plasma IGF-I increased from d -3 to 17 (linear, P < 0.05) and was increased for S vs A on d 9 (P < 0.06) and d 15 (P < 0.03), and for S vs P (P < 0.02) on d 9. A disease challenge &times; time interaction was observed (P < 0.05) for average daily gain as it decreased for S (.62 kg) vs A (1.38 kg; P < 0.01) and P (.95 kg; P < 0.07) from d 0 to 3. A disease challenge&times;ctime interaction was observed for retained nitrogen (N; P