Application of a Beta Regression Model for Covariate Adjusted ROC
- 1 Baylor University, United States
Copyright: © 2020 Xing Meng and J.D. Tubbs. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
The Receiver Operating Characteristic (ROC) curve and the area under the ROC (AUC) are widely used in determining the diagnostic capability of a binary classification procedure. Since the test performance is affected by covariates, the ROC and AUC have been utilized in a Generalized Linear Regression (GLM) setting. In this study, we revisit a problem where the AUC regression model was used in a clinical study with discrete covariates by considering ROC regression models with both discrete and continuous covariates. The two ROC regression models are based upon a widely used parametric model and a recently published model based upon fitting the placement values with the beta distribution. The two methods are illustrated using data from a clinic study.
- Placement Values
- Beta Regression
- ROC Regression