Research Article Open Access

Oral Administration of Gelatin Hydrolysate Reduces Clinical Signs of Canine Osteoarthritis in a Double-Blind, Placebo-Controlled Trial

A. C. Beynen1, H. W. Van Geene1, H. V. Grim1, P. Jacobs1 and T. Van der Vlerk1
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American Journal of Animal and Veterinary Sciences
Volume 5 No. 2, 2010, 102-106

DOI: https://doi.org/10.3844/ajavsp.2010.102.106

Submitted On: 17 April 2010 Published On: 30 June 2010

How to Cite: Beynen, A. C., Van Geene, H. W., Grim, H. V., Jacobs, P. & Van der Vlerk, T. (2010). Oral Administration of Gelatin Hydrolysate Reduces Clinical Signs of Canine Osteoarthritis in a Double-Blind, Placebo-Controlled Trial. American Journal of Animal and Veterinary Sciences, 5(2), 102-106. https://doi.org/10.3844/ajavsp.2010.102.106

Abstract

Problem statement: There are indications that the intake of gelatin hydrolysate has a beneficial impact on the clinical signs of osteoarthritis in dogs. Data from a controlled trial were required to substantiate these indications. Approach: A double-blind, placebo-controlled trial with privately owned dogs was carried out to assess the efficacy of a preparation of gelatin hydrolysate in the treatment of osteoarthritis. With the use of a questionnaire, the clinical signs were evaluated by the owners. For a period of 8 weeks, the test dogs daily received 10 g of gelatin hydrolysate; as a placebo, soya protein isolate was used. The supplements were mixed with the diet; all dogs were fed on the same dry food. There were 15 dogs per treatment group. Results: The administration of gelatin hydrolysate significantly improved activity (vitality) and significantly reduced stiffness and lameness. Conclusion: Gelatin hydrolysate is commonly used as a component of human foods and is generally considered as safe. It is suggested that a dose of about 2.5% in a dry food would be beneficial for dogs with osteoarthritis.

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Keywords

  • Dog
  • osteoarthritis
  • gelatin
  • hydrolysate