OnLine Journal of Biological Sciences

DNA Vaccination Associated with Eliminating Inheritance Risks during Embryo Development: A Review

Ria Margiana

DOI : 10.3844/ojbsci.2016.107.114

OnLine Journal of Biological Sciences

Volume 16, Issue 2

Pages 107-114


The process of immunization using modified DNA is essential whenever scientists desire to trigger an artificial response in the host’s body to improve immunity. The use of DNA vaccines awakens the somatic cells of the host to produce antigens that will assist the body to prepare to fight infections through preventive measures triggered by the vaccines. These biological inventions have assisted in controlling diseases as well as eliminating some health conditions. Scientific analyses have shown how the plasmid DNA could trigger an artificial immune response in living organisms when associated with the antigens that are plasmid-encoded. Such revelations have demonstrated that this invention has a possible therapeutic application as vaccination to prevent numerous pathogens and their related infections. This paper reviews the concept of DNA vaccination and its effects on embryogenesis. The paper first discusses an overview of DNA vaccines and relates it to the production and expression processes. The effects on embryo development have also been described. This review also explains the advantages and disadvantages related to DNA vaccines’ administration and the mechanisms employed to enhance plasmid effectiveness.


© 2016 Ria Margiana. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.