OnLine Journal of Biological Sciences

Cell Surface Receptor Theory of Disease Infectivity; Body's Defence and Normal Body Functioning in Living Things

Utoh-Nedosa and Uchechukwu Anastasia

DOI : 10.3844/ojbsci.2011.76.83

OnLine Journal of Biological Sciences

Volume 11, Issue 2

Pages 76-83

Abstract

Problem statement: A study of the pattern of Candida spp. infection of the human body and the mode and pattern of reaction of the human body to this infection showed that disease infectivity and self healing by plants followed the same procedures and patterns. Approach: A comparism of these procedures and patterns of natural self- healing of disease infection by the human body and plants/plant parts with the cutaneous Candida spp. killing and elimination procedures and patterns of Vernonia amygdalina leaf extract, showed that cell surface receptors are the sites through which disease infects the body and also the sites at which the body is defended. They are also the sites where activities which result in normal body functioning are carried out. The mode and patterns of Cutaneous Candida infection in a human subject and its containment by the body was examined and photographed. The disease infection and self healing procedures and patterns of plants were also examined in comparism with those of their healthy counterparts and photographed. The findings from the observations on disease infectivity and natural body’s defence patterns and procedures of the plant parts studied and those of the human body in reaction to Candida spp. infection were compared with those of the Candida spp. killing procedures and patterns of aqueous and Arachis hypogeal oil extract of Vernonia amygdalina leaf. Results: The findings of this study also showed that disease-infective organisms gain access to the body of a host through attachment to the cell surface receptors of that host which are placed linearly and are interconnected by channels. The results of the study also indicated that living organisms have a main endogenous substance that mediates both their body’s defence and their normal physiological functioning which is therefore the owner of the cell surface receptor. Other endogenous substances which participate in normal body functioning/body’s defence or in body’s offence like hormones, drugs, toxins and venoms interact with the body through the cell surface receptors (which are the receptors of the main mediator of the body’s defence and normal functioning of an organism. Substances like lidocaine (an anesthetic); tetrodotoxin and afflatoxin therefore inhibit or antagonize the normal functioning of the body by blocking the excitatory actions of the mediator of normal body functioning. Conclusion: The study concludes that cell surface receptors are the sites through which infective organisms attach to the body of a host and that the cell surface receptor has two reactive terminals or heads with which endogenous and exogenous substances like drugs and infective pathogens interact with the body of a living organism.

Copyright

© 2011 Utoh-Nedosa and Uchechukwu Anastasia. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.