OnLine Journal of Biological Sciences

Preliminary Study on Immunomodulatory Effect of Sarang-Semut Tubers Myrmecodia tuberosa and Myrmecodia pendens

Triana Hertiani, Ediati Sasmito, Sumardi and Maria Ulfah

DOI : 10.3844/ojbsci.2010.136.141

OnLine Journal of Biological Sciences

Volume 10, Issue 3

Pages 136-141

Abstract

Problem Statement: Sarang-Semut tubers, Myrmecodia tuberosa and M. pendens (Rubiaceae) are both medicinal plants originating from Papua which have broad range of therapeutic values including those to improve vitality. Nevertheless, no scientific proof is available so far on their immunomodulatory effect. The purpose of this study was to reveal the potency of Sarang-Semut tubers as immunomodulatory agent by evaluating their effects on Balb/c mice lymphocytes proliferation and macrophage phagocytosis by in vitro techniques. Approach: Bioactivity assays were performed on the raw extracts and fractions. Extracts were obtained by macerating the pulverized samples in ethanol 95%, followed by successive fractionation to yield n-hexane, ethyl acetate and water fractions. Series of extracts and fractions were made to concentration 10, 20, 50 and 100

Copyright

© 2010 Triana Hertiani, Ediati Sasmito, Sumardi and Maria Ulfah. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.