Current Research in Dentistry

Factor Analysis on Onset of Ventilator-Associated Pneumonia for Inpatients in the Intensive Care Unit

Takafumi Ooka, Yoshimasa Okamatsu, Yuriko Ando, Hiroshi Takano, Youhei Tsuru, Motoko Ida, Shouji Hironaka, Yasafumi Maruoka and Yoshiharu Mukai

DOI : 10.3844/crdsp.2015.7.12

Current Research in Dentistry

Volume 6, Issue 1

Pages 7-12


The objective of the presentstudy is toassess risk factors" at the stage of proofs, including oralhealth status, with the development of VAP in perioperative patients, with thefinal aim of the establishing oral health management systems in acute carehospitals. Of the patients who were admitted to the Intensive Care Unit (ICU)of our university hospital from January to December 2011 and who underwent oralintubation, 11 patients who received a diagnosis of VAP (nine men and twowomen) and 11 control patients (eight men and three women) were selected assubjects for the present study. We first investigated the disease names listedin the medical records of subjects in the VAP group and then selected patientswho had the same diseases as the control group subjects. Within one day afteradmission to the ICU, a dentist evaluated the oral health status of thepatients and the lips, teeth, oral mucosa, gingiva, tongue and xerostomia werescored (0-12) based on the criteria of the Revised Oral Assessment Guide(ROAG). Furthermore, six items (operative duration, BMI, length of ICU stay,Acute Physiology and Chronic Health Evaluation (APACHE II) score and length ofventilator used) were extracted from patient medical records and investigated.The items were used as independent variables and their relationship with thedevelopment of VAP was examined by regression analysis. Oral health care wasperformed by a nurse four times per day, using a standard toothbrush or spongebrush. Moreover, this study was approved by the Ethics Committee of theDepartment of Dentistry in our university. When each factor was compared in theVAP group and the control group, the VAP group showed significantly higherscores for oral health status, length of ICU stay and length of ventilatorused. Furthermore, when the development of VAP and the relationships with eachfactor were examined by regression analysis, a significant relationship withoral health status, operative duration, BMI and length of ventilator use wasseen. The results of the present study suggest the possibility of variousfactors being involved in the development of VAP in orally intubated patients,such as the oral health status of the patient. Appropriate oral health care canaid the prevention of perioperative pulmonary infections.


© 2015 Takafumi Ooka, Yoshimasa Okamatsu, Yuriko Ando, Hiroshi Takano, Youhei Tsuru, Motoko Ida, Shouji Hironaka, Yasafumi Maruoka and Yoshiharu Mukai. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.