Glucan Supplementation Regulates Secretory Immunity and Stress
Richter Josef, Stiborová Ivana, Král Vlastimil, Svozil Vladimir, Vetvicka Vaclav and Rajnohová Dobiáová Lucie
DOI : 10.3844/ajisp.2017.81.85
American Journal of Immunology
Volume 13, 2017
Sixty-six children were supplemented with beta glucan and dietary nucleotides, another 63 children served as negative control. We evaluated the effects of these supplements on several aspects of secretory immunity such as levels of secretory IgA (SIgA), albumin and SIgA/albumin ratio. In addition, in order to monitor effects of physical challenges and compensatory treatments on stress and reparation of immunity, we measured levels of salivary cortisol. We found significant effects of supplementation with beta glucan on secretory IgA in children with increased physical challenge. To fully explain these findings, we will need to add additional indicators of stress and salivary immunity.
© 2017 Richter Josef, Stiborová Ivana, Král Vlastimil, Svozil Vladimir, Vetvicka Vaclav and Rajnohová Dobiáová Lucie. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.