Immunomodulatory Activity of Argan Oil (Argania spinosa L)
Youcef Necib, Ahlem Bahi, Sakina Zerizer, Cherif Abdennour and Mohamed Salah Boulakoud
DOI : 10.3844/ajisp.2013.85.87
American Journal of Immunology
Volume 9, Issue 3
Immunomodulatory activity of Argan oil was evaluated on phagocytic activity by carbon clearance test. Adult Albinos Wistar rats randomly divided into four groups, were the first was served as a control, while animals of treatment group were given Argan oil at dose of: 2.5, 5 and 10 mL kg-1 by gavage respectively 10 days before injected the carbon ink suspension. In carbone clearance test, Argan oil exhibited significantly phagocytic index dose-dependent against control group, indicating stimulation of the reticulo-endothelial system. Present study thus reveals that argan oil holds promise as immunomodulatory agent, which act by stimulating dose dependent phagocytic function.
© 2013 Youcef Necib, Ahlem Bahi, Sakina Zerizer, Cherif Abdennour and Mohamed Salah Boulakoud. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.