American Journal of Immunology

Atopic Dermatitis and Type 1 Diabetes Mellitus in Iranian Children

Elham Ahmadi, Zahra Rahnama and Ali R. Tehrani

DOI : 10.3844/ajisp.2009.98.100

American Journal of Immunology

Volume 5, Issue 3

Pages 98-100


Problem statement: Atopic diseases, including asthma, eczema and allergic rhinitis, are characterized by a chronic inflammatory reaction mediated by T helper 2 cells, while type 1 diabetes mellitus is mediated by T helper 1 cells. Approach: The aim of this study was to compare the prevalence of atopic dermatitis between children with type 1 diabetes mellitus and age-matched controls. We conducted a case-control study enrolling 150 cases with type 1 diabetes mellitus between 2-20 years from pediatric endocrine out patient clinic and 450 controls randomly selected from the general population matched on sex and age. The diagnosis of atopic dermatitis was determined for patients and controls by the Hanifin and Rajka


© 2009 Elham Ahmadi, Zahra Rahnama and Ali R. Tehrani. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.