American Journal of Immunology

Advanced Oxidation Protein Products in Aged with Dementia

Melike Erol Demirbilek, Nedret Kilic, H. Ferhan Komurcu and K. Okhan Akin

DOI : 10.3844/ajisp.2007.52.55

American Journal of Immunology

Volume 3, 2007

Pages 52-55

Abstract

The role of increased oxidative stress in the development of oxidative protein damage in aging have been reported. There is an important role of oxidative stress on development of dementia. Advanced oxidation protein products (AOPPs) are novel markers of oxidative stress. The aim of this study was to compare AOPP levels in healthy aged person and aged person with dementia. AOPP levels were in the control group 83.36 ± 35.51 μmol/L, and 178.78 ± 110.50 μmol/L in the group with dementia. This elevation in the group with dementia was statistically significant (p<0.05). AOPP might be a useful novel indicator of oxidative stress in dementia.

Copyright

© 2007 Melike Erol Demirbilek, Nedret Kilic, H. Ferhan Komurcu and K. Okhan Akin. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.