American Journal of Infectious Diseases

Detection of Hepatitis C Virus Resistant Mutants in the era of Direct Acting Antivirals

Livia Maria Gonçalves Rossi and Paula Rahal

DOI : 10.3844/ajidsp.2014.179.183

American Journal of Infectious Diseases

Volume 10, Issue 4

Pages 179-183


Hepatitis C Virus (HCV) infects millions of people and represents an important public health problem in different regions of the world. Drug resistance is a major challenge for HCV-infection related control. Importantly, the arrival of a plethora of novel, more powerful drugs has revolutionized the field of HCV treatment. Here, we discuss the relevance of identification of HCV resistant mutants from a clinical standpoint. The advantage and limitations of molecular testing in clinical setting is presented.


© 2014 Livia Maria Gonçalves Rossi and Paula Rahal. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.