American Journal of Infectious Diseases

Clinical and Sociodemographic Risk Factors for Tuberculosis in Human Immunodeficiency Virus Infected Patients

Paz-Ayar Nibardo, Jose Antonio Mata-Marin, Jesus Gaytan-Martinez, Gloria Huerta-Garcia and Benjamin Acosta-Cazares

DOI : 10.3844/ajidsp.2013.142.147

American Journal of Infectious Diseases

Volume 9, Issue 4

Pages 142-147

Abstract

To identify clinical and sociodemographic factors associated with the risk of tuberculosis in HIV-infected patients. A case-control study in a cohort of HIV-infected patients. Cases: patients coinfected with HIV and pulmonary or extrapulmonary tuberculosis. Controls: no clinical tuberculosis and PPD negative, matched for age and sex. Primary data were obtained from medical records and personal interviews. We identified 47 cases and 94 controls. The main risk factors identified were: underweight (malnutrition) (BMI ≤ 18.49), abscence of antiretroviral therapy, CD4 + cells count ≤ 199 cells/mm3, RNA HIV-1 viral load ≥ 100,000 copies/mL. Tuberculosis is associated to multiple risk factors in HIV infected patients, clinical factors are more important that sociodemographic ones. CD4+ cells count < 200 cells/µL, malnutrition IMC < 18.9 and RNA HIV-1 viral load > 100,000 copies/mL are associated with tuberculosis in HIV infected patients.

Copyright

© 2013 Paz-Ayar Nibardo, Jose Antonio Mata-Marin, Jesus Gaytan-Martinez, Gloria Huerta-Garcia and Benjamin Acosta-Cazares. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.