Mortality among HIV-Infected Patients in Resource Limited Settings: A Case Controlled Analysis of Inpatients at a Community Care Center
Nirmala Rajagopalan, Joyce B. Suchitra, Anita Shet, Zafar K. Khan, Julio Wigdahl, Michael R. Nonnemacher, Jeffrey M. Jacobson and Brian Wigdahl
DOI : 10.3844/ajidsp.2009.219.224
American Journal of Infectious Diseases
Volume 5, Issue 3
Problem statement: Despite massive national efforts to scale up Antiretroviral Therapy (ART) access in India since 2004, the AIDS death rate was 17.2 per 100,000 persons during 2003-2005. In the era of HAART in resource poor settings, it is imperative to understand and address the causes of AIDS related mortality. This collaborative study aimed at defining the predictors of mortality among people living with HIV/AIDS (PLHA) admitted during 2003-2005 to the Freedom Foundation (FF) Care and Support facility, Bangalore, India. Approach: Fifty consecutively selected HIV-infected patients who died during the study period and 50 HIV-infected patients matched by age, gender, route of transmission, nutrition status and stage of disease who survived at least 12 months post-ART were included in this study. The impact on mortality by factors such as: Hemoglobin, CD4+T lymphocyte counts, weight loss and Opportunistic Infections (OIs) were studied. Statistical analyses were done by Chi-square, Fisher
© 2009 Nirmala Rajagopalan, Joyce B. Suchitra, Anita Shet, Zafar K. Khan, Julio Wigdahl, Michael R. Nonnemacher, Jeffrey M. Jacobson and Brian Wigdahl. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.