Estimating HIV-1 Incidence Using the Serologic Testing Algorithm for Recent HIV Seroconversion at HIV Counseling and Testing Centers in the City of São Paulo, Brazil
Katia Cristina Bassichetto, Denise Pimentel Bergamaschi, Maria Amelia Veras, Maria Cecilia Araripe Sucupira, Fabio Mesquita and Ricardo Sobhie Diaz
DOI : 10.3844/ajidsp.2008.257.261
American Journal of Infectious Diseases
Volume 4, Issue 4
The network of HIV counseling and testing centers in São Paulo, Brazil is a major source of data used to build epidemiological profiles of the client population. In this study, HIV-1 incidence from November of 2000 to April of 2001 was estimated, comparing recently infected individuals to those with long-standing infection in terms of epidemiological and socio-behavioral aspects. To identify recent infection, less sensitive ELISA was employed. The overall incidence of HIV-1 infection among the clients was 0.53/100/year (95% CI: 0.31-0.85/100/year): 0.77/100/year for males (95% CI: 0.42-1.27/100/year) and 0.22/100/year (95% CI: 0.05-0.59/100/year) for females. Overall HIV-1 prevalence was 3.2% (95% CI: 2.8-3.7%), being 4.0% among males (95% CI: 3.3-4.7%) and 2.1% among females (95% CI: 1.6-2.8%). Recent infections accounted for 15% of the total (95% CI: 10.2-20.8%). Recent infection correlated with being younger and male (p = 0.019). Therefore, recent infection was more common among younger males and older females.
© 2008 Katia Cristina Bassichetto, Denise Pimentel Bergamaschi, Maria Amelia Veras, Maria Cecilia Araripe Sucupira, Fabio Mesquita and Ricardo Sobhie Diaz. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.