American Journal of Bioinformatics

Applying Information Theory Analysis for the Solution of Biomedical Data Processing Problems

David Blokh and Ilia Stambler

DOI : 10.3844/ajbsp.2014.17.29

American Journal of Bioinformatics

Volume 3, Issue 1

Pages 17-29

Abstract

The use of information-theoretical methods can be highly valuable for the solution of biomedical data processing problems. Some of the problems that can be solved by those methods include: The assessment of the influence of diagnostic parameters, biomarkers and risk factors, on the emergence of disease; the discretization of diagnostic parameters; the analysis of a combined influence of a group of parameters; the partition of a group of diagnostic parameters according to the amount of diagnostic information contained in those parameters; the analysis of the parameters' heterogeneity or variability and more. To illustrate the solution of those problems, we use a data base on diabetes patients. There are grounds to believe that an increasing application of information-theoretical methodologies in biomedical research will lead to significant practical dividends for diagnosis and therapy.

Copyright

© 2014 David Blokh and Ilia Stambler. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.