The Progress of BMP4 on the Role of Ocular Development and Eye Diseases
Liang Jiaming, Wang Qian, Liu Xiaohe, Wang Shurong and Zhang Yan
DOI : 10.3844/ajbbsp.2017.58.62
American Journal of Biochemistry and Biotechnology
Volume 13, Issue 2
Bone morphogenetic protein belongs to the transforming growth factor beta superfamily, is a unique ectopic cartilage and bone inducing activity of acidic protein. As one of the members of BMPs family, the formation and development of BMP4 in many organizations. In ocular tissue, BMP4 not only promotes the differentiation and development of different eye cells, but also plays an important role in ocular diseases. In this study, the recent advances in the study of BMP4 in ocular tissues are summarized and the function of BMP4 in different developmental stages of eye is briefly reviewed.
© 2017 Liang Jiaming, Wang Qian, Liu Xiaohe, Wang Shurong and Zhang Yan. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.