Process Intensification for Production and Recovery of Biological Products
Hamideh Vaghari, Maryam Eskandari, Vahideh Sobhani, Aydin Berenjian, Yuanda Song and Hoda Jafarizadeh-Malmiri
DOI : 10.3844/ajbbsp.2015.37.43
American Journal of Biochemistry and Biotechnology
Volume 11, Issue 1
Bioprocesses are important biological reactions which need several sophisticated methods and equipment to produce many novel and important compounds which some of them are traditionally produced by synthetic chemical reactions. In bioprocesses, the products are often produced in a dilute environment and finally they require a high purity. Because of that, downstream processes are usually included a large number of separation steps. Size and capital costs of the equipment are two main limitations of using bioprocesses at industrial scale. Bioprocess intensification by minimizing, substitution, moderation and simplification of the methods and equipment, drastically leads to sustainable processes. This study looks at intensification of the emerging equipment and operational methods and their advantages to lead smaller and cleaner bioprocess plants which in turn, increases production efficiency and quality and decreases byproducts formation, capital cost and energy consumption.
© 2015 Hamideh Vaghari, Maryam Eskandari, Vahideh Sobhani, Aydin Berenjian, Yuanda Song and Hoda Jafarizadeh-Malmiri. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.