American Journal of Biochemistry and Biotechnology

Detection of Cancer Biomarkers with Nanotechnology

Lei Zhang, Dan Lv, Weijun Su, Yanhua Liu, Yanan Chen and Rong Xiang

DOI : 10.3844/ajbbsp.2013.71.89

American Journal of Biochemistry and Biotechnology

Volume 9, Issue 1

Pages 71-89

Abstract

Early detection of cancer biomarkers with high precision is critically important for cancer therapy. A variety of sensors based on different nanostructured materials have attracted intensive research interest due to their potential for highly sensitive and selective detection of cancer biomarkers. This review covers the use of a variety of nanostructured materials, including carbon nanotubes, silicon nanowires, gold nanoparticles and quantum dots, in the fabrication of sensors. Emphases are placed on how the detection systems work and what detection limits can be achieved. Some assays described in this review outperform established methods for cancer biomarker detection. It is highly promising that these sensors would soon move into commercial-scale production and find routine use in hospitals.

Copyright

© 2013 Lei Zhang, Dan Lv, Weijun Su, Yanhua Liu, Yanan Chen and Rong Xiang. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.