Ginger Supplementation Enhances Working Memory of the Post-Menopause Women
Naritsara Saenghong, Jintanaporn Wattanathorn, Terdthai Tong-Un, Supaporn Muchimapura, Nawanant Piyavhatkul, Chuleratana Bunchonglikitkul and Tanwarat Kajsongkram
DOI : 10.3844/ajassp.2011.1241.1248
American Journal of Applied Sciences
Volume 8, Issue 12
Problem statement: Cognitive impairment is one important problem in post-menopausal women. Although hormone therapy can improve this condition, it also produces adverse effect. Recent findings showed that this condition could be mitigated by the herb. Ginger or Zingiber officinale Roscoe, a plant in a family of Zingiberaceae, was previously demonstrated the neuroprotection and cognitive enhancing effects. Therefore, this study was set up to determine whether ginger rhizome extract could improve attention and working memory of the post-menopausal women. Approach: Sixty healthy post-menopausal women were randomly assigned to receive either placebo or standardized plant extract at doses of 400 and 800 mg once daily for 3 months. After the assessment of biographic information, they were evaluated the working memory and cognitive function using computerized battery test and the auditory oddball paradigm of event related potential before and after 3-month of intervention. Results: The ginger treated group decreased N100 and P300 latencies but increased N100 and P300 amplitudes in accompany with the enhanced working memory including the power of attention, continuity of attention, speed and quality of memory. Conclusion: Our results suggested that ginger is the potential cognitive enhancer for post-menopausal women. However, further researches are still required.
© 2011 Naritsara Saenghong, Jintanaporn Wattanathorn, Terdthai Tong-Un, Supaporn Muchimapura, Nawanant Piyavhatkul, Chuleratana Bunchonglikitkul and Tanwarat Kajsongkram. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.