Synthesis and Characterization of Gold Nanoparticles by Tryptophane
Azim Akbarzadeh, Davood Zare, Ali Farhangi, Mohammad Reza Mehrabi, Dariush Norouzian, Shahram Tangestaninejad, Majid Moghadam and Nasim Bararpour
DOI : 10.3844/ajassp.2009.691.695
American Journal of Applied Sciences
Volume 6, Issue 4
Problem statement: Preparation and synthesis of gold nanoparticles with small size and suitable stability is very important and applicable particularly in medicine. In this study, we have prepared gold nanoparticles by chemical reduction method employing L-Tryptophane as a reducing agent for ionic gold. Approach: The gold nanoparticles are the most employed amongst the different metallic nanoparticles in the fields of nanomedicine and nanobiotechnology. Therefore, the employed method should provide suitable particle size, shape and particle distribution in order to obtain nanoparticles of high activity and efficiency indicating the importance of the technique. In this study, HAuCl4 .3H2O, L-Tryptophane and polyethyleneglycol (PEG) were used to produce AuCl-4 ions. They were acted as pre-material, reducing and stabilizing agents respectively. Results: The size, distribution and formation of gold nanoparticles were confirmed by Transmission Electron Microscopy (TEM) indicating the diameter of gold nanoparticles at the range of 10-25 nm and UV spectroscopy. The formed nanoparticles showed the highest absorption at 518 nm. Conclusion: The gold nanoparticles were stable in PEG1000. Since these nanoparticles have suitable size distribution they can be considered as a suitable candidate to be employed in nanomedicine and nanobiotechnology.
© 2009 Azim Akbarzadeh, Davood Zare, Ali Farhangi, Mohammad Reza Mehrabi, Dariush Norouzian, Shahram Tangestaninejad, Majid Moghadam and Nasim Bararpour. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.