A Case-Control Study of Effect of Opium Addiction on Myocardial Infarction
Behzad Azimzade-Sarwar, Gholamreza Yousefzade and Shahin Narooey
DOI : 10.3844/ajassp.2005.1134.1135
American Journal of Applied Sciences
Volume 2, Issue 7
Ischemic Heart Disease (IHD) and Myocardial Infarction (MI) are one of the most important disease which cause mortality and morbidity. Opioid peptides and exogenous opioid such as morphine are known to exert an important cardiovascular effect. To study effect of opium addiction to incidence of MI. A Case-Control study was designed in Kerman university. 150 patients with MI was admitted to CCU and 150 matched patients admitted in surgical wards evaluate from cardiovascular risk factor and opium addiction. Analysis of data suggested no difference between two groups (P>0.05). But smoking OR = 2.45, hypertension OR = 2.65, Diabetes mellitus OR = 1.82 and Hypercholesterolemia OR = 3.16 were a risk factor for MI. Effect of opium in IHD has controversial. But recent of study defined that opioid peptides have a cardioprotective effect. Many exact and longitudinal studies should design for this purpose.
© 2005 Behzad Azimzade-Sarwar, Gholamreza Yousefzade and Shahin Narooey. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.